Sickle Cell

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by NancyAriel2015
Last updated 7 years ago

Discipline:
Science
Subject:
Cell Biology
Grade:
9

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Sickle Cell

Statistics:-Children are born with sickle cell disease; its not contagious-Occurs when children inherits two sickle hemoglobin genes, one from each parent.-About 2 million Americans have sickle cell traits

Sickle Cell :- Sickle cell anemia is an inherited blood disorder.-About 100,000 people in the United States are affected by this disease. -Mostly in African Americans

Sickle Cell Anemia

Its Orgin Name?-its orginal name is "Sickle Cell Anemia". Anemia is a condiontion in which the blood doesn't have enough healthy red blood cells. Sickle is the name of the shape that the cell forms when abnormal.

Causes of Sickle Cell:- Sickle call causes red blood cells to form in a crescent shape, like a sickle.- Severe Pain and Premenant Damage:- brain damage - heart - lungs- kidneys-liver- bones- spleen (abdominal organ)

More Causes:-Severe pain is an emergency called acute sickle cell crisis. -Infection and dehydration are commone triggers.

Hemoglobin:-One thing sickle cell is also caused by is hemoglobin and its genetic; if abnormal..-Hemoglobin is a protein responsible for transporting oxygen in the blood vertebrates. This causes the shape of the blood cell.

Normal vs. Abnormal Blood Cells:-Normal Cellsblood cells are round and flexible. Which enables them to travel through small blood vessels to deliver osygen to all parts of the body. -Abnormal (Sickle) Cellssickle shape red blood cells break apart easily, causing anemia. Which means they dont travel as easily as normal cells.-sickle blood cells also dump together and stick to walls blocking regular blood flow.

Things to Know: - Regular blood cells live up tp 120 days- Sickle blood cells live only 10-20 days- 20k to 200k U.S. cases per year

Treatments:-opioid pain medications (morphine)-Anti-inflammatory medications (ibuprofen)-Antibiotics for infection -Oxygen (adequate oxygen)-Intraverious or oral fluidsCure:-Bone marrow transplant offers the only potential

Life ExpectancyIn 1973, the average life span for people with sickle cell was 14 years. But with technology now the average life span in 50 years, maybe even more.

How Sickle Cell is detectedA simple blood test done at any time during a persons life span can detect whether he or she has sickle cell.How ever early diagnosis is important.In the U.S. all sates mandate testing for SCA as part of their newborn screening programs.

Symptoms- Infections - pain- fatigue- Slow growth- Vision problems

When to see a doctor- Swelling in hands or - pale skin or nail beds - fever- Any signs or symptoms of stroke

Most serious dangers are acute syndrom, long term damage to major organs, and stroke

Citationswww.mayoclinic.org/diseases-conditions/sickle-cell-anemia/basics/definitions/con-20019348http://www.sicklecelldisease.org/index.cfm?page=about-scdhttps://www.genome.gov/10001219


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