Robertsonian Translocation

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robertsonian translocation [rob′ərtsō′nē·ən] the exchange of entire chromosome arms, with the break occurring at the centromere, usually between two nonhomologous acrocentric chromosomes. It produces one large, metacentric chromosome and one extremely small chromosome. The latter carries little genetic material and may be lost through successive cell divisions, leading to a reduction in total chromosome number.

Robertsonian TranslocationKevin Dunnaway 3rd Hour

Robertsonian translocation can prevent birth or cause no real damage. It can result in trisomy or down syndrome. It can be inherited by a carrier having two chromosomes from different pairs combine. One could undergo in vitro fertilization (IVF) to treat it.