Phenylephrine Hydrochloride

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Phenylephrine Hydrochloride

Phenylephrine Hydrochloride

Reference:Truven Health AnalyticsMicromedex ® SolutionsVanderbilt University Medical Center

Adverse EffectsCardiovascular effects: Angina, cardiac dysrhythmia, and decreased cardiac output.Dermatologic effects: contract dermatitis, necrosis and pruritus. Gastrointestinal effects: abdominal angina, epigastric pain and vomiting.Immunologic effects: anaphylaxis, cell-mediated immune reaction and hypersensitivity reaction. Musculoskeletal effect: neck pain.Neurologic effects: Headache, transient and tremor.Ophthalmic effects: Blurred vision, conjunctivitis, and eye/vision finding.Respiratory effects:Pulmonary edema, sneezing, and nasal congestion.

Phenylephrine hydrochloride, a synthetic sympathomimetic agent, is a powerful postsynaptic alpha-receptor agonist with minimal effect on the beta-receptors of the heart. It exhibits a rapid and moderately extended vasoconstrictor and mydriatic action. Its action in the heart includes elevation of the heart rate and reduction of cardiac output.

Drug Class: Adrenergic and AlkylarylamineRoutes: Injection, Intravenous, Mucous Membrane, Nasal, Ophthalmic, Oral, Rectal and Topical

Drug Classes & Routes


Neo-SynephrineNeofrinNostrilPrefrin LiquifilmOcu-PhrinVicks SinexMydfrinAK-Dilate

Contraindications and Precautions

Trade Names

How does the medication work?

GlaucomaHypotension, during anesthesiaHypotension - ShockMydriasis inductionNasal congestion, Nasal formulationNasal congestion, Oral formulationPosterior synechiae - Uveitis

Contraindications1) Anatomical narrow-angle2) Arteriosclerotic cardiovascular or cerebrovascular disease, severe; in infants and elderly 3) Ventricular tachycardia

Precautions1) Cardiovascular: Use extreme caution in patients with brachycardia.2) Dermatologic: Avoid extravasation as this can cause necrosis3) Neurologic: Blood pressure response to adrenergic drugs may be increased in patients with autonomic dysfunction

4-Way No DripAnu-Med NFChildrens Triaminic Thin StripsGood Neighbor Pharmacy Nasal Decongestant PEMedi-First Non-Pseudo Sinus DecongestantNasal Decongestant PERite Aid Nasal Decongestant PESudafed PETopCare Nose Drops Vazculep

How it is supplied

How to use a nasal spary


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