Myasthenia Gravis (MG)

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by NunezA16
Last updated 7 years ago

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Health & Fitness
Subject:
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Myasthenia Gravis (MG)

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Myasthenia gravis affects both the nervous and muscular systems. The weakening of skeletal muscles is caused by the self-destruction of the neuromuscular junction (Penn, A., ' Kaminski, H., 2012). The thymus, which controls the production of lymphocytes that fight off diseases, is also affected and becomes hyperactive (Myasthenia Gravis, n.d.).

"Myasthenia gravis is not directly inherited nor is it contagious. Occasionally, the disease may occur in more than one member of the same family" (Myasthenia Gravis Fact Sheet, 2014). The disease most commonly affects women under 40 years old and men over 60 years old. With treatment, patients can lead normal lives and possibly go into remission. In severe cases, respiratory failure may occur and lead to death (Myasthenia Gravis Fact Sheet, 2014).

Myasthenia Gravis (MG)

Myasthenia gravis is a chronic autoimmune disease that is characterized by the weakening of skeletal muscles. Antibodies are produced to fight against the neuromuscular junction (Myasthenia Gravis, n.d.).

Research

Contagiousness, Hereditariness, and Prognosis

Treatments

Lewis, J. (n.d.). Facts About Myasthenia Gravis. Retrieved from http://mdaustralia.org.au/wp-content/uploads/2012/07/011_myasthenia-gravis-2012.pdfKenny, T. (2014, March 24). Myasthenia Gravis. Retrieved from http://www.patient.co.uk/health/myasthenia-gravis-leafletMyasthenia Gravis. (n.d.). Retrieved from http://my.clevelandclinic.org/services/neurological_institute/neuromuscular-center/diseases-conditions/myasthenia-gravisMyasthenia Gravis Fact Sheet. (2014, November 12). Retrieved from http://www.ninds.nih.gov/disorders/myasthenia_gravis/detail_myasthenia_gravis.htmPenn, A., ' Kaminski, H. (2012, July 16). EPublications. Retrieved from http://womenshealth.gov/publications/our-publications/fact-sheet/myasthenia-gravis.htmlVarious Diseases ' Disorders of the Muscular System. (n.d.). Retrieved from https://cyhsanatomy1.wikispaces.com/Various Diseases ' Disorders of the Muscular System

Resources

"MG affects two to seven out of every 10,000 people..." (Lewis J., n.d.).

Interesting Facts

The National Institute of Neurological Disorders and Stroke (NINDS) is using technological advances to better understand this disease. Researches have a better understanding of the neuromuscular junction and have a general idea of the effects of the thymus on immunity. However, researches are still unsure why the autoimmune response is triggered and how the thymus contributes to myasthenia gravis.Scientists are currently studying how a thymectomy (removal of the thymus) could be a possible cure (Myasthenia Gravis Fact Sheet, 2014).

Epidemiology

Image retrieved from: http://www.nhs.uk/conditions/Myasthenia-gravis/Pages/Introduction.aspxhttp://www.nhs.uk/conditions/Myasthenia-gravis/Pages/Introduction.aspx

Cholinesterase inhibitors help improve nerve signals and muscular strength. Immunosuppressive drugs help slow down the production of abnormal antibodies. Thymectomies help improve symptoms and can sometimes cure MG. Plasmapheresis is the exchanging of blood plasma to remove antibodies from the bloodstream. Intravenous immunoglobulin prevents the antibodies from attacking the neuromuscular junction (Penn, A., ' Kaminski, H., 2012).

Images

Systems Affected

Image retrieved from: https://cyhsanatomy1.wikispaces.com/Various%20Diseases%20'%20Disorders%20of%20the%20Muscular%20System

https://www.youtube.com/watch?v=wKHY22nUsqY


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