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by deewilly24
Last updated 7 years ago

Health & Fitness

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Street Names--Duramorph, M, Miss Emma, Monkey, Roxanol and White Stuff.

Morphine(5α,6α)-7,8-didehydro- 4,5-epoxy-17-methylmorphinan-3,6-diol

Long Term Symptoms morphine also can lead to physical dependence. This can also include tolerance and addiction. Individuals taking prescribed opioid medications should be given these medications under appropriate medical supervision and should be supervised when discontinuing use to mitigate withdrawal symptoms.

Short Term Symptoms:Morphine affects regions of the brain that mediate what we perceive as pleasure, resulting in initial feelings of euphoria. Morphine can also produce drowsiness, cause constipation, and, depending upon the amount taken, depress breathing. Taking a large single dose could cause severe respiratory depression, coma or death.

How is Morphine used?Morphine is often used before or after surgery to alleviate severe pain. Morphine and other opioids act by attaching to specific proteins called opioid receptors, which are found in the brain, spinal cord, and gastrointestinal tract. When these compounds attach to certain opioid receptors in the brain and spinal cord, they can effectively change the way a person experiences pain.



Treatment?Tolerance and physical dependence development to morphine in mice can be prevented by concomitant administration of cycloheximide. The fact that the rate of synthesis of brain 5-hydroxytryptamine (5HT) increases with tolerance to morphine suggests that the protein involved may be associated with 5HT synthesis. Inhibition of this synthesis with p-chlorophenylalanine markedly decreases tolerance and physical dependence development to morphine.

Length Of EffectHow long morphine lasts depends on the form of morphine and the method it was taken. There is a form of morphine sulfate that comes in a modified release tablet that can last 12 hours.


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