Hemophilia

In Glogpedia

by mwooden
Last updated 5 years ago

Discipline:
Science
Subject:
Biology
Grade:
11

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Hemophilia

Hemophilia

What is it?

How do you get it?/What causes it?

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What are the symptoms & effects?

Statistics/Interesting Facts

How do you treat it?

• replacement therapy: injecting concentrations of clotting factor VIII (for hemophilia A) or clotting factor IX (for hemophilia B) into the vein• desmopressin (DDAVP): man-made hormone given as an injection or nasal spray that stimulates the release of stored factor VIII• antifibrinolytic medicines: help keep blood clots from breaking down

• disorder that slows down the blood clotting process• two major types: hemophilia A and hemophilia B• hemophilia A: gene mutation (insertion, substitution, or missing) of F8 gene, deficiency in the protein coagulation factor VIII• hemophilia B: gene mutation (insertion, substitution, or missing) in the F9 gene, deficiency in protein coagulation factor IX

• inherited in an x-linked recessive pattern• acquired hemophilia (not by genetics): body makes antibodies that attack and disable coagulation factor VIII

• spontaneous bleeding• prolonged bleeding after injury• many large bruises• swelling of joints caused by internal bleeding• nosebleeds without a cause

source: bravoblooddonor.org

source: koate-dvi.com

source: healthresearchfunding.org

Skyler's Hemophilia Treatment

Impact on Life• frequent trips to the hospital or carefully monitored home treatment • limited physical activity• expensive treatment


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