[2011] mason: Grave's Disease

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[2011] mason: Grave's Disease

Graves Disease

Graves' ophthalmopathy

Symptoms

Treatments for Graves' disease include radioactive iodine, antithyroid medications such as methimazole (Tapazole) and propylthiouracil (PTU), andbeta blockers; in some patients, surgery is done

About 30 percent of people with Graves' disease show some signs and symptoms of a condition known as Graves' ophthalmopathy. In Graves' ophthalmopathy, inflammation and other immune system events affect muscles and other tissues around your eyes. The resulting signs and symptoms may include:Bulging eyes (exophthalmos)Gritty sensation in the eyesPressure or pain in the eyesPuffy or retracted eyelidsReddened or inflamed eyesLight sensitivityDouble visionVision loss

Is an immune system that results in the overproduction of hormones produced in the thyroid. Because thyroid hormones affect a number of different body systems, signs and symptoms associated with Graves' disease can be wide ranging and significantly influence your overall well-being. Although Graves' disease may affect anyone, it's more common among women and before the age of 40.

The primary treatment goals are to inhibit the overproduction of thyroid hormones and lessen the severity of symptoms.Common signs and symptoms of Graves' disease include:Anxiety and irritabilityA fine tremor of your hands or fingersHeat sensitivity and an increase in perspiration or warm, moist skinWeight loss, despite normal eating habitsEnlargement of your thyroid gland (goiter)Change in menstrual cyclesErectile dysfunction or reduced libidoFrequent bowel movementsBulging eyes (Graves' ophthalmopathy)Thick, red skin usually on the shins or tops of the feet (Graves' dermopathy)Rapid or irregular heartbeat (palpitations)

The thyroid is a small gland in the front of the neck. It makes hormones called T3 and T4 that regulate how the body uses energy. Thyroid hormone levels are controlled by the pituitary, which is a pea-sized gland in the brain. It makes thyroid stimulating hormone (TSH), which triggers the thyroid to make thyroid hormone. With Graves' disease, the immune system makes antibodies that act like TSH, causing the thyroid to make more thyroid hormone than your body needs. This is called an overactive thyroid or hyperthyroidism. An overactive thyroid causes every function of the body to speed up, such as heart rate and the rate your body turns food into energy. Graves' disease is one cause of overactive thyroid.

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