Genetic disorders: Breast Cancer

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Genetic disorders: Breast Cancer

Genetic Disorders:Breast CancerBy: Brooke Bennett

What is Breast Cancer?Normal cells usually divide and grow in order to replace damaged tissue. Sometimes, though, mechanisms that help regulate cell growth stop working and cell division goes out-of-control. This crazy, out of control growth is known as cancer. People who develop breast cancer usually don't have any history of the disease though their family. Only about 5-10 people who have breast cancer receive it through inherited genetic factors. If the disease was inherited through genes, it usually is either a BRCA1 gene or a BRCA2 gene.

BRCA1 and BRCA2The genes BRCA1 and BRCA2 are what scientists call " tumor supressed genes." This is because these genes control the cell growth of the body. Gene BRCA1 is located in the 17th chromosome of the body and the gene BRCA2 is located in the 13th chromosome. These genes help heal and replace broken DNA in cells. Women who inherite mutated copies of these genes have a higher risk of "accumulated mutations" or cancer.

WHAT?This might seem crazy, but yes, men can have breast cancer!

How do people get breast cancer?A child who inherites just one mutated gene from the mother or father can have an increased risk of breast cancer. This might seem scary, but not every child who inherites the mutated BRCA1 gene or BRCA2 gene immediately get breast cancer, it just increases the risk of having breast cancer. Out of 100 females who inherite a mutated gene, 60 females over the age of 50 will recieve cancer.By the age of 70, 80 females will recieve breast cancer.

If the cancer in the milk ducts of the breast (that's usually where breast cancer is formed) spreads to other parts of the body, this is known as ductal carcinoma.

Interesting Facts

Breast cancer is usually formed in the milk area of the breast. The two main areas it usually formes is the lobules and the milk ducts. Sometimes though, cancer is formed in the stormal tissue of the breast, the fatty part. Treating breast cancer the minute it is found is super important to everyone. FIGHT FOR THE CURE!

Why Breast Cancer?When I found out about this genetic disorder project, I immediately wanted to do breast cancer. I wanted to do this because there was plenty of research and it was familiar to me. But, that wasn't the only reason. During one normal science class one day, I found out that Ms. Stellema's mother had breast cancer twice. I felt guilty that I hadn't known. I wanted this project to be special to her and I. Ms. Stellema, I just want you to know you are a very strong person for going through all this. Your mother was very strong as well, even through the fight to save her DNA and genes.

Learn.GeneticsWebsiteNational down to the breast cancer video, or the DNA video, that's where I got my info.)


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