Frederick Sanger

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by treyjones1
Last updated 4 years ago

Discipline:
Science
Subject:
Scientific Biographies

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Frederick Sanger

Frederick Sanger

Fred was born13 August 1918 inRendcomb, Gloucestershire, England

His notable awards wereFRS,Nobel Prize in Chemistry, Royal Medal,Gairdner Foundation International Award,William Bate Hardy Prize,Copley Medal,Louisa Gross Horwitz Prize,and Nobel Prize in Chemistry

He died on November 19, 2013 at age 95Cambridge, Cambridgeshire, England

Glog by: Trey Jones

He had two other siblings. His brother, Theodore and his sister May . His father had worked as an Anglican medical missionary in China but returned to England because of sicknesses.

he is Known forAmino acid sequence of insulin Sanger sequencingSanger Centre

In 1936 Sanger went to St John's College, Cambridge to study natural sciences. His father had attended the same college. For his courseshe took physics, chemistry, biochemistry and math but struggled with physics and math.

in 1951 Sanger was a member of the external staff of the Medical Research Council and when they opened the Lab of Molecular Biology in 1962, he moved from his labs in the Biochemistry Department of the university to the top floor of the new building. He became head of the Protein Chemistry division.

when he started sequencing DNA. He looked at different ways of using DNA polymerase I from E. coli to copy single stranded DNA.In 1975 together with Alan Coulson he published a sequencing procedure using DNA polymerase with radiolabelled nucleotides that he called the "Plus and Minus" technique.

Sanger married Margaret Joan Howe in 1940. They had three children.Robin, born in 1943, Peter born in 1946 and Sally Joan born in 1960.He said that his wife had contributed more to his work than anyone else


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