FOP

Fibrodysplasia Ossificans Progressiva

Extremely rare disease of the connective tissueMutation of the body's repair mechanisms which causes fibrous tissue to be ossified spontaneously or when damanged. In many cases, injuries can cause joints to be permanently frozen in place

Overview

No known effective treatmentSurgical removal of the extra bone growths has been shown to cause the body to "repair" the affected area with more bone

Any trauma to the muscles, such as a fall or invasive medical procedure may trigger episodes of myositis and rapid ossification of the injured area.

Treatment

occurs

in

million people worldwide

FOP is misdiagnosed 80% of the time, often as cancer. This results in unnecessary invasive procedures which make FOP worse.

Diagnosis

the only characteristsic showing evidence of FOP is malformation of the big toe

Life expectancy=40 yearsCause of death is normally thoracic insufficiency syndrome