Epigenetics Poster

by yangzz
Last updated 7 years ago


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Epigenetics Poster

Background - 1904: “Fly” lab at Columbia University to study genetic variations.- Discoveries of genetics and chromosomal inheritance came out of his lab.- January 1910: Discovery of the first useful fruit fly mutation. Flies usually have red eyes but they found a male with white eyes.- Thomas Hunt Morgan chose to do a simple breeding analysis to find out more about white eyes by observing the transmission of genetic traits through successive generations.1904: “Fly” lab at Columbia University to study genetic variations.

How epigenetics or reprogramming results in this phenomenon - Drosophila melanogaster - the classic genetic model organism for epigenetic research- Two well-studied epigenetic phenomena in Drosophila melanogaster: 1. Position-effect variegation (PEV): results in the clonal silencing of genes juxtaposed to heterochromatin 2. Polycomb group (PcG) and trithorax group (trxG) proteins

Implication(s) of the phenomenon on the organism- Renato Paro did an experiment on white-eyed fruit flies > Surrounding temperature of embryos raised from 25°C to 37°C → red-eyed offspring > Following generations are partly-red eyed, not white- eyed according to rules of genetics- Environment affects inheritance!! > Temperature treatment changes the eye colour of the fruit fly → change can be passed on to offsprings over several generations- However, DNA sequence remains the same for both white-eyed parents and red-eyed offsprings > explained by the concept of epigenetics

Epigenetics in Drosphila melanogasterDone by: Vanessa Ching and Hazel Lau (Class 2)

References[1] Access Excellence @ the National Health Museum Research Center, Sex-linked Inheritance: Drosophila. Retrieved 11 October 2014, from http://www.accessexcellence.org/RC/VL/GG/sex.php. [2] DNA from the Beginning, Fruit fly genetics: Chromosomes carry genes. Retrieved 11 October 2014, from http://www.dnaftb.org/10/animation.html.[3] Keith R. Benson (June 2001). Perspectives (Vol. 2), T.H. Morgan’s resistance to the chromosome theory.[4] Stockholm University (Wenner-Gren Institute for Experimental Biology), Epigenetics. Retrieved 11 October 2014, from http://www.su.se/cmlink/stockholms-universitet-naturvetenskapliga-fakulteten/wenner-grens-institut-nod/the-wenner-gren-institute-for-experimental-biology/research/research-groups/mattias-mannervik/projects/epigenetics-1.60146. [5] Swiss Federal Institute of Technology Zurich, DNA isn’t Everything. Retrieved 11 October 2014, from http://www.ethlife.ethz.ch/archive_articles/090401_Epigenetik_mas/index_EN.



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