Down Syndrome

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by ariaheath
Last updated 5 years ago

Health & Fitness

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Down Syndrome

Down syndrome is caused by an error in cell division called "nondisjunction." Nondisjunction results in an embryo with three copies of chromosome 21 instead of the usual two.


Trimony 21- a pair of 21st chromosomes in either the sperm or the egg fails to separate. As the embryo develops, the extra chromosome is replicated in every cell of the body. This type of Down syndrome, which accounts for 95% of cases, is called trisomy 21. Mosaicism- Mosaicism is diagnosed when there is a mixture of two types of cells, some containing the usual 46 chromosomes and some containing 47. Those cells with 47 chromosomes contain an extra chromosome 21. This case is accounted for 1%. Translocation-In translocation, which accounts for about 4% of cases of Down syndrome, the total number of chromosomes in the cells remains 46; however, an additional full or partial copy of chromosome 21 attaches to another chromosome, usually chromosome 14.

3 different types

One in every 691 babies in the United States are born with Down Syndrome, making it the most common genetic condition.


Down Syndrome

Glog by: Aria Heath

What causes Down Syndrome?

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