Central Nervous System

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Last updated 3 years ago

Discipline:
Science
Subject:
Human Anatomy
Grade:
7

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Central Nervous System

Prion=Potienacous+Infectous

PRIONS

The Prion is 100% protien. This was very puzzling to scientists, because it lacks nucleic acid, making it very different to bacteruim and viruses. The first sign of prions was in Scrappie, a TSE, that causes sheep and goats to develope odd behavoir habits, like scraping away their wool. The first theory was the desease was a virus encased in protien, but Stanley Prusiner, a US neurologist, disproved it, because enzymes that combat nucleic acid had little effect, while the oppisite was true for the enzymes that dissolve protiens. Scientists reasoned that a desease must have nucleic acid, to reproduce. Stanley identified a gene within patients of Gerstmann-Strassler-Scheinker syndrome, a TSE in humans, that produces a protein very simular to the scrapie protien. This allows the protien to create more of its kind. His discovery has debated but most scientist believed that he was correct in his findings. We know know that proins also infect other protiens, causing the virus to spread.

AKA Laughing Death

KURU

1985 - Scrapie developes in sheep1990- A new form of Creutzfeldt-Jakob desease breaks out in Great Britain, Killing 19 people in their younger years. The victims aquired the desease from eating beef from cows with mad cow desease.1992 - Scrapie is at its peak.1997 - Stanley Prusiner is awarded the nobel prize for his work with prions.2005- Eric Kandel Compares Prions to the protiens that help create long term memories. 2006- Scientists discover that prions uses heathy protiens to infect other protiens.

Kuru is an endemic in Papua Ne Guinea. This desease was spread by the practice of eating the brains of the dead. However it has since died off, after the practice was discontinued. A victim of Kuru will lose cordination, and devolope dementia shortly after. The victim will, as its nickname suggests, laugh maniacally for no apparent reason. Before they die, the will become calm, and quite, without reacting. They will sit like that without moving untill they die, Either from skin ulcer, from sitting in the same place for a long time, or their lungs will fill up with blood, killing them first. The desease will fill this course in 3 months to a year.

The Human Brain

PRIONSTake the Quiz!

Central Nervous System

PRIONSTimeline

The central nervous system consists of the brain and spinal cord. The spinal cord floats in a clear liquid known as cerebrospinal fluid, and is cased in a sequence of vertabre connected by thick ligaments. This is the path that nerve impulses travel to reach the brain. If part of the spinal cord is damaged, the body loses control of every thing below that point.

TSETransmissable Spongiform Encephalophathies

The Central Nervous system takes the information from the senses, and then sends insctructions back out. The Brain consists of two hemispheres, that each control the contrasting side of the body. The hemispheres are covered in wrinkled gray matter, called the Cerebral Cortex , and are conected by a core of white matter. The dominant hemisphere controlls higher functions, such as langauge, and analyzing. The non-dominate hemisphere controls simple functions such as face recognition.

A prion, under a microscope.

Homeostasis is all about balence. To keep homeostasis the body must mantian stable internal conditions. For example, when your body gets overheated you sweat. It is the job of the nervous system to manage these changes, and mantian the balence, like a scale.

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