Next-Gen

Alzheimer's Diseasae and Cell Signaling

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by st5ymjnxz
Last updated 1 year ago

Discipline:
Science
Subject:
Genetics
Grade:
11,12

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Alzheimer's Disease and Cell Signaling

"The Alzheimers association feels confident that DIAN-TU, along with the other 4 on going prevention trials, will accelerate the scientifical coomunity's ability to determine whether an early intervention can dely or stop Alzheimers disease."

Current direction of research

Alzheimer's is a progressive disease that destroys memory and other importanat mental functions. there are more than 5 million U.S. cases per year. Alzheimers can last for years or be lifelong.

What is Alzheimers disease?

Incorrect mechanisimThe G protein and the receptors all work perfectly fine. However, neurotransmitters (the ligand) deteriorate before they can reach the G protien to acivate the rest of the cell processes. Many of these reasosns are unknown and being researched.

Correct mechanism Normal G protien receptor waits for a Ligand to connect and activate it. Thus causing the signal to be the target to create a molecular reaction for the cell.

Alexis RodriguezAlden Lee

"Scientist have identified a network of 9 genes that play a key role in Alzheimers"

The part of the brain that this disease affects is along the cell's signaling pathway of the G-protein receptor pathway or the Gated Ion Channels. During the G-protein receptor pathway, a signal from the ligand is received by a G-protein and then transferred down into the alpha section of the G-protein. The alpha section of the G-protein then moves with the signal inside it to an inactive protein which then uses GTP to activate the protein and do its cellular function. The signals are received by the brain which then enacts its functions to conduct the daily life of the organism. The brain gets these signals by ligands which carry the message to the signal receptors. The ligands decay in Alzheimer's disease which cuts off the brain from functioning and ultimately causing it to decay.The part of the brain that this disease affects is along the cell's signaling pathway of the G-protein receptor pathway or the Gated Ion Channels. During the G-protein receptor pathway, a signal from the ligand is received by a G-protein and then transferred down into the alpha section of the G-protein. The alpha section of the G-protein then moves with the signal inside it to an inactive protein which then uses GTP to activate the protein and do its cellular function. The signals are received by the brain which then enacts its functions to conduct the daily life of the organism. The brain gets these signals by ligands which carry the message to the signal receptors. The ligands decay in Alzheimer's disease which cuts off the brain from functioning and ultimately causing it to decay.


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